SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency
SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The role of sirtuins (SIRTs) in cancer biology has been the focus of recent research. The similarities between underlying pathways involved in the induction of pluripotent stem cells and transformation of cancer cells revealed the role of SIRTs in cellular reprogramming. Seven SIRTs have been identified in mammals and downregulation of SIRT2 was fo...
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Full title
SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6117269
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6117269
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-018-0920-3
