Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Aging is the strongest risk factor for Alzheimer’s disease (AD), although the underlying mechanisms remain unclear. The chromatin state, in particular through the mark H4K16ac, has been implicated in aging and thus may play a pivotal role in age-associated neurodegeneration. Here we compare the genome-wide enrichment of H4K16ac in the lateral tempo...
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Full title
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6124498
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6124498
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-018-0101-9
