Development of a gut microbe-targeted non-lethal therapeutic to inhibit thrombosis potential
Development of a gut microbe-targeted non-lethal therapeutic to inhibit thrombosis potential
About this item
Full title
Author / Creator
Roberts, Adam B. , Gu, Xiaodong , Buffa, Jennifer A. , Hurd, Alex G. , Wang, Zeneng , Zhu, Weifei , Gupta, Nilaksh , Skye, Sarah M. , Cody, David B. , Levison, Bruce S. , Barrington, William T. , Russel, Matthew W. , Reed, Jodie M. , Duzan, Ashraf , Lang, Jennifer M. , Fu, Xiaoming , Li, Lin , Myers, Alex J. , Rachakonda, Suguna , DiDonato, Joseph A. , Brown, J. Mark , Gogonea, Valentin , Lusis, Aldons J. , Garcia-Garcia, Jose Carlos and Hazen, Stanley L.
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
Trimethylamine-N-oxide (TMAO), a microbiota-dependent metabolite derived from trimethylamine (TMA)-containing nutrients that are abundant in a Western diet, enhances both platelet responsiveness and in vivo thrombosis potential in animal models and predicts incident atherothrombotic event risks in clinical studies. Here, utilizing a mechanism-based...
Alternative Titles
Full title
Development of a gut microbe-targeted non-lethal therapeutic to inhibit thrombosis potential
Authors, Artists and Contributors
Author / Creator
Gu, Xiaodong
Buffa, Jennifer A.
Hurd, Alex G.
Wang, Zeneng
Zhu, Weifei
Gupta, Nilaksh
Skye, Sarah M.
Cody, David B.
Levison, Bruce S.
Barrington, William T.
Russel, Matthew W.
Reed, Jodie M.
Duzan, Ashraf
Lang, Jennifer M.
Fu, Xiaoming
Li, Lin
Myers, Alex J.
Rachakonda, Suguna
DiDonato, Joseph A.
Brown, J. Mark
Gogonea, Valentin
Lusis, Aldons J.
Garcia-Garcia, Jose Carlos
Hazen, Stanley L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6129214
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6129214
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0128-1
