Copy number signatures and mutational processes in ovarian carcinoma
Copy number signatures and mutational processes in ovarian carcinoma
About this item
Full title
Author / Creator
Macintyre, Geoff , Goranova, Teodora E. , De Silva, Dilrini , Ennis, Darren , Piskorz, Anna M. , Eldridge, Matthew , Sie, Daoud , Lewsley, Liz-Anne , Hanif, Aishah , Wilson, Cheryl , Dowson, Suzanne , Glasspool, Rosalind M. , Lockley, Michelle , Brockbank, Elly , Montes, Ana , Walther, Axel , Sundar, Sudha , Edmondson, Richard , Hall, Geoff D. , Clamp, Andrew , Gourley, Charlie , Hall, Marcia , Fotopoulou, Christina , Gabra, Hani , Paul, James , Supernat, Anna , Millan, David , Hoyle, Aoisha , Bryson, Gareth , Nourse, Craig , Mincarelli, Laura , Sanchez, Luis Navarro , Ylstra, Bauke , Jimenez-Linan, Mercedes , Moore, Luiza , Hofmann, Oliver , Markowetz, Florian , McNeish, Iain A. and Brenton, James D.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The genomic complexity of profound copy number aberrations has prevented effective molecular stratification of ovarian cancers. Here, to decode this complexity, we derived copy number signatures from shallow whole-genome sequencing of 117 high-grade serous ovarian cancer (HGSOC) cases, which were validated on 527 independent cases. We show that HGS...
Alternative Titles
Full title
Copy number signatures and mutational processes in ovarian carcinoma
Authors, Artists and Contributors
Author / Creator
Goranova, Teodora E.
De Silva, Dilrini
Ennis, Darren
Piskorz, Anna M.
Eldridge, Matthew
Sie, Daoud
Lewsley, Liz-Anne
Hanif, Aishah
Wilson, Cheryl
Dowson, Suzanne
Glasspool, Rosalind M.
Lockley, Michelle
Brockbank, Elly
Montes, Ana
Walther, Axel
Sundar, Sudha
Edmondson, Richard
Hall, Geoff D.
Clamp, Andrew
Gourley, Charlie
Hall, Marcia
Fotopoulou, Christina
Gabra, Hani
Paul, James
Supernat, Anna
Millan, David
Hoyle, Aoisha
Bryson, Gareth
Nourse, Craig
Mincarelli, Laura
Sanchez, Luis Navarro
Ylstra, Bauke
Jimenez-Linan, Mercedes
Moore, Luiza
Hofmann, Oliver
Markowetz, Florian
McNeish, Iain A.
Brenton, James D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6130818
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6130818
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-018-0179-8
