20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and...
20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats
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England: Portland Press Ltd
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English
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England: Portland Press Ltd
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We hypothesized that vascular actions of 20-hydroxyeicosatetraenoic acid (20-HETE), the product of cytochrome P450 (CYP450)-dependent ω-hydroxylase, potentiate prohypertensive actions of angiotensin II (ANG II) in Cyp1a1-Ren-2 transgenic rats, a model of ANG II-dependent malignant hypertension. Therefore, we evaluated the antihypertensive effective...
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Full title
20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6131326
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6131326
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ISSN
0144-8463
E-ISSN
1573-4935
DOI
10.1042/BSR20171496
