A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
An immune fitness model for tumours under checkpoint blockade immunotherapy is proposed, through which the authors show that the presentation and recognition properties of dominant neoantigens distributed over tumour subclones are predictive of response in melanoma and lung cancer cohorts.
Predicting tumour response to immunotherapy
Response...
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Full title
A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6137806
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6137806
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature24473