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BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6140509

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export

About this item

Full title

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (37), p.E8668-E8677

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The close integration of the MAPK, PI3K, and WNT signaling pathways underpins much of development and is deregulated in cancer. In principle, combinatorial posttranslational modification of key lineage-specific transcription factors would be an effective means to integrate critical signaling events. Understanding how this might be achieved is centr...

Alternative Titles

Full title

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6140509

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6140509

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1810498115

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