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CYP24A1 depletion facilitates the antitumor effect of vitamin D3 on thyroid cancer cells

CYP24A1 depletion facilitates the antitumor effect of vitamin D3 on thyroid cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6143870

CYP24A1 depletion facilitates the antitumor effect of vitamin D3 on thyroid cancer cells

About this item

Full title

CYP24A1 depletion facilitates the antitumor effect of vitamin D3 on thyroid cancer cells

Author / Creator

Publisher

Greece: Spandidos Publications

Journal title

Experimental and therapeutic medicine, 2018-10, Vol.16 (4), p.2821-2830

Language

English

Formats

Publication information

Publisher

Greece: Spandidos Publications

More information

Scope and Contents

Contents

It has been demonstrated that 25-hydroxyvitamin-D3-24-hydroxylase (CYP24A1) is a key enzyme that neutralizes vitamin D activity, which may have an anti-tumor effect. Therefore, the aim of the current study was to explore the effect of the active metabolite of vitamin D, 1,25-dihydroxyvitamin D (1,25-D3) on thyroid cancer cells following the downreg...

Alternative Titles

Full title

CYP24A1 depletion facilitates the antitumor effect of vitamin D3 on thyroid cancer cells

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6143870

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6143870

Other Identifiers

ISSN

1792-0981

E-ISSN

1792-1015

DOI

10.3892/etm.2018.6536

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