The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer
The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that regulates a plethora of downstream signaling pathways essential for cell migration, proliferation and death, processes that are exploited by cancer cells during malignant progression. These well-established tumorigenic activities, together with its high expression and activity in dif...
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Full title
The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6148276
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6148276
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ISSN
2157-9024
E-ISSN
2157-9024
DOI
10.1038/s41389-018-0083-1