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The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer

The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6148276

The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer

About this item

Full title

The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer

Publisher

London: Nature Publishing Group UK

Journal title

Oncogenesis (New York, NY), 2018-09, Vol.7 (9), p.73-19, Article 73

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that regulates a plethora of downstream signaling pathways essential for cell migration, proliferation and death, processes that are exploited by cancer cells during malignant progression. These well-established tumorigenic activities, together with its high expression and activity in dif...

Alternative Titles

Full title

The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6148276

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6148276

Other Identifiers

ISSN

2157-9024

E-ISSN

2157-9024

DOI

10.1038/s41389-018-0083-1

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