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GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis

GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6152935

GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis

About this item

Full title

GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2018-09, Vol.561 (7722), p.263-267

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Starvation poses a fundamental challenge to cell survival. Whereas the role of autophagy in promoting energy homeostasis in this setting has been extensively characterized
1
, other mechanisms are less well understood. Here we reveal that glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibits coat protein I (COPI) transport by targeting a...

Alternative Titles

Full title

GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6152935

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6152935

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0475-6

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