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Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6153602

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines

About this item

Full title

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Pflügers Archiv, 2018-10, Vol.470 (10), p.1555-1567

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Mediated through the combined action of STIM proteins and Orai channels, store-operated Ca
2+
entry (SOCE) functions ubiquitously among different cell types. The existence of multiple STIM and Orai genes has made it difficult to assign specific roles of each STIM and Orai homolog in mediating Ca
2+
signals. Using CRISPR/Cas9 gene editin...

Alternative Titles

Full title

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6153602

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6153602

Other Identifiers

ISSN

0031-6768

E-ISSN

1432-2013

DOI

10.1007/s00424-018-2165-5

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