Monoamine oxidase‐A is a novel driver of stress‐induced premature senescence through inhibition of p...
Monoamine oxidase‐A is a novel driver of stress‐induced premature senescence through inhibition of parkin‐mediated mitophagy
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
Cellular senescence, the irreversible cell cycle arrest observed in somatic cells, is an important driver of age‐associated diseases. Mitochondria have been implicated in the process of senescence, primarily because they are both sources and targets of reactive oxygen species (ROS). In the heart, oxidative stress contributes to pathological cardiac...
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Full title
Monoamine oxidase‐A is a novel driver of stress‐induced premature senescence through inhibition of parkin‐mediated mitophagy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6156293
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6156293
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ISSN
1474-9718
E-ISSN
1474-9726,1474-9728
DOI
10.1111/acel.12811