TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs
TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Activation of HIV-1 reservoirs and induction of anti-HIV-1 T cells are critical to control HIV-1 rebound after combined antiretroviral therapy (cART). Here we evaluated in humanized mice (hu-mice) with persistent HIV-1 infection the therapeutic effect of TLR3 agonist and a CD40-targeting HIV-1 vaccine, which consists of a string of 5 highly conserv...
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Full title
TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6159955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6159955
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ISSN
0021-9738,1558-8238
E-ISSN
1558-8238
DOI
10.1172/JCI99005