Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology
Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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The polymerase-associated factor 1 (Paf1) complex is a general transcription elongation factor of RNA polymerase II, which is composed of five core subunits, Paf1, Ctr9, Cdc73, Leo1, and Rtf1, and functions as a diverse platform that broadly affects gene expression genome-wide. In this study, we solved the 2.9-Å crystal structure of the core region...
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Full title
Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6176576
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6176576
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1812256115
