The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in t...
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
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Author / Creator
Klughammer, Johanna , Kiesel, Barbara , Roetzer, Thomas , Fortelny, Nikolaus , Nemc, Amelie , Nenning, Karl-Heinz , Furtner, Julia , Sheffield, Nathan C. , Datlinger, Paul , Peter, Nadine , Nowosielski, Martha , Augustin, Marco , Mischkulnig, Mario , Ströbel, Thomas , Alpar, Donat , Ergüner, Bekir , Senekowitsch, Martin , Moser, Patrizia , Freyschlag, Christian F. , Kerschbaumer, Johannes , Thomé, Claudius , Grams, Astrid E. , Stockhammer, Günther , Kitzwoegerer, Melitta , Oberndorfer, Stefan , Marhold, Franz , Weis, Serge , Trenkler, Johannes , Buchroithner, Johanna , Pichler, Josef , Haybaeck, Johannes , Krassnig, Stefanie , Mahdy Ali, Kariem , von Campe, Gord , Payer, Franz , Sherif, Camillo , Preiser, Julius , Hauser, Thomas , Winkler, Peter A. , Kleindienst, Waltraud , Würtz, Franz , Brandner-Kokalj, Tanisa , Stultschnig, Martin , Schweiger, Stefan , Dieckmann, Karin , Preusser, Matthias , Langs, Georg , Baumann, Bernhard , Knosp, Engelbert , Widhalm, Georg , Marosi, Christine , Hainfellner, Johannes A. , Woehrer, Adelheid and Bock, Christoph
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Glioblastoma is characterized by widespread genetic and transcriptional heterogeneity, yet little is known about the role of the epigenome in glioblastoma disease progression. Here, we present genome-scale maps of DNA methylation in matched primary and recurring glioblastoma tumors, using data from a highly annotated clinical cohort that was select...
Alternative Titles
Full title
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
Authors, Artists and Contributors
Author / Creator
Kiesel, Barbara
Roetzer, Thomas
Fortelny, Nikolaus
Nemc, Amelie
Nenning, Karl-Heinz
Furtner, Julia
Sheffield, Nathan C.
Datlinger, Paul
Peter, Nadine
Nowosielski, Martha
Augustin, Marco
Mischkulnig, Mario
Ströbel, Thomas
Alpar, Donat
Ergüner, Bekir
Senekowitsch, Martin
Moser, Patrizia
Freyschlag, Christian F.
Kerschbaumer, Johannes
Thomé, Claudius
Grams, Astrid E.
Stockhammer, Günther
Kitzwoegerer, Melitta
Oberndorfer, Stefan
Marhold, Franz
Weis, Serge
Trenkler, Johannes
Buchroithner, Johanna
Pichler, Josef
Haybaeck, Johannes
Krassnig, Stefanie
Mahdy Ali, Kariem
von Campe, Gord
Payer, Franz
Sherif, Camillo
Preiser, Julius
Hauser, Thomas
Winkler, Peter A.
Kleindienst, Waltraud
Würtz, Franz
Brandner-Kokalj, Tanisa
Stultschnig, Martin
Schweiger, Stefan
Dieckmann, Karin
Preusser, Matthias
Langs, Georg
Baumann, Bernhard
Knosp, Engelbert
Widhalm, Georg
Marosi, Christine
Hainfellner, Johannes A.
Woehrer, Adelheid
Bock, Christoph
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6181207
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6181207
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0156-x