Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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YAP/TAZ are nuclear effectors of the Hippo pathway regulating organ growth and tumorigenesis. Yet, their function as transcriptional regulators remains underinvestigated. By ChIP-seq analyses in breast cancer cells, we discovered that the YAP/TAZ transcriptional response is pervasively mediated by a dual element: TEAD factors, through which YAP/TAZ...
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Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6186417
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6186417
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/ncb3216
