Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with...
Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Background
Human cancers can be classified based on gene signatures quantifying the degree of cell proliferation and tissue remodelling (PR). However, the specific factors that drive the increased tissue remodelling in tumours are not fully understood. Here we address this question using colorectal cancer as a case study.
Methods
We reanal...
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Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6189192
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6189192
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-018-0253-0