Co-regulatory networks of human serum proteins link genetics to disease
Co-regulatory networks of human serum proteins link genetics to disease
About this item
Full title
Author / Creator
Emilsson, Valur , Ilkov, Marjan , Lamb, John R , Finkel, Nancy , Gudmundsson, Elias F , Pitts, Rebecca , Hoover, Heather , Gudmundsdottir, Valborg , Horman, Shane R , Aspelund, Thor , Shu, Le , Trifonov, Vladimir , Sigurdsson, Sigurdur , Manolescu, Andrei , Zhu, Jun , Olafsson, Örn , Jakobsdottir, Johanna , Lesley, Scott A , To, Jeremy , Zhang, Jia , Harris, Tamara B , Launer, Lenore J , Zhang, Bin , Eiriksdottir, Gudny , Yang, Xia , Orth, Anthony P , Jennings, Lori L and Gudnason, Vilmundur
Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: The American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Proteins circulating in the blood are critical for age-related disease processes; however, the serum proteome has remained largely unexplored. To this end, 4137 proteins covering most predicted extracellular proteins were measured in the serum of 5457 Icelanders over 65 years of age. Pairwise correlation between proteins as they varied across indiv...
Alternative Titles
Full title
Co-regulatory networks of human serum proteins link genetics to disease
Authors, Artists and Contributors
Author / Creator
Ilkov, Marjan
Lamb, John R
Finkel, Nancy
Gudmundsson, Elias F
Pitts, Rebecca
Hoover, Heather
Gudmundsdottir, Valborg
Horman, Shane R
Aspelund, Thor
Shu, Le
Trifonov, Vladimir
Sigurdsson, Sigurdur
Manolescu, Andrei
Zhu, Jun
Olafsson, Örn
Jakobsdottir, Johanna
Lesley, Scott A
To, Jeremy
Zhang, Jia
Harris, Tamara B
Launer, Lenore J
Zhang, Bin
Eiriksdottir, Gudny
Yang, Xia
Orth, Anthony P
Jennings, Lori L
Gudnason, Vilmundur
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6190714
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6190714
Other Identifiers
ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.aaq1327
