TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enh...
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
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Publisher
England
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Language
English
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England
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Contents
Tumour-associated macrophages are abundant in many cancers, and often display an immune-suppressive M2-like phenotype that fosters tumour growth and promotes resistance to therapy. Yet, macrophages are highly plastic and can also acquire an anti-tumorigenic M1-like phenotype. Here, we show that R848, an agonist of the toll-like receptors TLR7 and T...
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Full title
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6192054
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6192054
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E-ISSN
2157-846X
DOI
10.1038/s41551-018-0236-8
