Mechanobiology of YAP and TAZ in physiology and disease
Mechanobiology of YAP and TAZ in physiology and disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Key Points
Mechanical signals are fundamental regulators of cell behaviour, but how mechanical cues are sensed and transduced at the molecular level to regulate gene expression has long remained enigmatic.
YAP and TAZ have been identified as conserved mechanotransducers, reading a very diverse set of mechanical cues, from shear stress to cell...
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Full title
Mechanobiology of YAP and TAZ in physiology and disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6192510
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6192510
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ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm.2017.87
