Transposon mutagenesis screen in mice identifies TM9SF2 as a novel colorectal cancer oncogene
Transposon mutagenesis screen in mice identifies TM9SF2 as a novel colorectal cancer oncogene
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
New therapeutic targets for advanced colorectal cancer (CRC) are critically needed. Our laboratory recently performed an insertional mutagenesis screen in mice to identify novel CRC driver genes and, thus, potential drug targets. Here, we define
Transmembrane 9 Superfamily 2
(
TM9SF2
) as a novel CRC oncogene. TM9SF2 is an understudied...
Alternative Titles
Full title
Transposon mutagenesis screen in mice identifies TM9SF2 as a novel colorectal cancer oncogene
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6193042
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6193042
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-33527-3
