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Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder...

Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6193489

Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects

About this item

Full title

Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Psychopharmacology, 2018-10, Vol.235 (10), p.3017-3030

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

(R,S)-Ketamine produces rapid, robust, and sustained antidepressant effects in major depressive disorder. Specifically, its pharmacological efficacy in treatment refractory depression is considered a major breakthrough in the field. However, the mechanism of action of ketamine’s rapid effect remains to be determined. In order to identify pathways t...

Alternative Titles

Full title

Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6193489

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6193489

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-018-4992-7

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