Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of...
Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Of late, nimbolide, a limonoid from the neem tree (
Azadirachta indica
) has gained increasing research attention owing to its potent antiproliferative and apoptosis-inducing effects. The present study was designed to investigate the effect of nimbolide on autophagy and the time point at which the phosphorylation status of GSK-3β and PI3K dic...
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Full title
Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6199248
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6199248
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-018-1126-4
