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C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6202324

C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

About this item

Full title

C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2018-10, Vol.37 (43), p.5780-5793

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Core 1 β1,3-galactosyltransferase (C1GALT1) controls the crucial step of GalNAc-type O-glycosylation and is overexpressed in various human malignancies. However, its role in head and neck squamous cell carcinoma (HNSCC) remains unclear. Here we demonstrate that C1GALT1 expression is upregulated in HNSCC tumors and is associated with adverse clinico...

Alternative Titles

Full title

C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6202324

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6202324

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-018-0375-0

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