Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under...
Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy
About this item
Full title
Author / Creator
Fumet, Jean-David , Richard, Corentin , Ledys, Fanny , Klopfenstein, Quentin , Joubert, Philippe , Routy, Bertrand , Truntzer, Caroline , Gagné, Andréanne , Hamel, Marc-André , Guimaraes, Camila Figueiredo , Coudert, Bruno , Arnould, Laurent , Favier, Laure , Lagrange, Aurélie , Ladoire, Sylvain , Saintigny, Pierre , Ortiz-Cuaran, Sandra , Perol, Maurice , Foucher, Pascal , Hofman, Paul , Ilie, Marius , Chevrier, Sandy , Boidot, Romain , Derangere, Valentin and Ghiringhelli, François
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background
No study has evaluated the predictive and prognostic role of CD8 and PD-L1 coexpression in non–small-cell lung cancer (NSCLC).
Methods
We analyzed RNA sequencing and/or immunohistochemistry staining in NSCLC patients from The Cancer Genome Atlas (
n
= 1016), and 34 metastatic NSCLC samples not treated by immunotherapy as...
Alternative Titles
Full title
Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy
Authors, Artists and Contributors
Author / Creator
Richard, Corentin
Ledys, Fanny
Klopfenstein, Quentin
Joubert, Philippe
Routy, Bertrand
Truntzer, Caroline
Gagné, Andréanne
Hamel, Marc-André
Guimaraes, Camila Figueiredo
Coudert, Bruno
Arnould, Laurent
Favier, Laure
Lagrange, Aurélie
Ladoire, Sylvain
Saintigny, Pierre
Ortiz-Cuaran, Sandra
Perol, Maurice
Foucher, Pascal
Hofman, Paul
Ilie, Marius
Chevrier, Sandy
Boidot, Romain
Derangere, Valentin
Ghiringhelli, François
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6203820
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6203820
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-018-0220-9
