Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel funct...
Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci
About this item
Full title
Author / Creator
Lilue, Jingtao , Doran, Anthony G. , Fiddes, Ian T. , Abrudan, Monica , Armstrong, Joel , Bennett, Ruth , Chow, William , Collins, Joanna , Collins, Stephan , Czechanski, Anne , Danecek, Petr , Diekhans, Mark , Dolle, Dirk-Dominik , Dunn, Matt , Durbin, Richard , Earl, Dent , Ferguson-Smith, Anne , Flicek, Paul , Flint, Jonathan , Frankish, Adam , Fu, Beiyuan , Gerstein, Mark , Gilbert, James , Goodstadt, Leo , Harrow, Jennifer , Howe, Kerstin , Ibarra-Soria, Ximena , Kolmogorov, Mikhail , Lelliott, Chris J. , Logan, Darren W. , Loveland, Jane , Mathews, Clayton E. , Mott, Richard , Muir, Paul , Nachtweide, Stefanie , Navarro, Fabio C. P. , Odom, Duncan T. , Park, Naomi , Pelan, Sarah , Pham, Son K. , Quail, Mike , Reinholdt, Laura , Romoth, Lars , Shirley, Lesley , Sisu, Cristina , Sjoberg-Herrera, Marcela , Stanke, Mario , Steward, Charles , Thomas, Mark , Threadgold, Glen , Thybert, David , Torrance, James , Wong, Kim , Wood, Jonathan , Yalcin, Binnaz , Yang, Fengtang , Adams, David J. , Paten, Benedict and Keane, Thomas M.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
We report full-length draft de novo genome assemblies for 16 widely used inbred mouse strains and find extensive strain-specific haplotype variation. We identify and characterize 2,567 regions on the current mouse reference genome exhibiting the greatest sequence diversity. These regions are enriched for genes involved in pathogen defence and immun...
Alternative Titles
Full title
Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci
Authors, Artists and Contributors
Author / Creator
Doran, Anthony G.
Fiddes, Ian T.
Abrudan, Monica
Armstrong, Joel
Bennett, Ruth
Chow, William
Collins, Joanna
Collins, Stephan
Czechanski, Anne
Danecek, Petr
Diekhans, Mark
Dolle, Dirk-Dominik
Dunn, Matt
Durbin, Richard
Earl, Dent
Ferguson-Smith, Anne
Flicek, Paul
Flint, Jonathan
Frankish, Adam
Fu, Beiyuan
Gerstein, Mark
Gilbert, James
Goodstadt, Leo
Harrow, Jennifer
Howe, Kerstin
Ibarra-Soria, Ximena
Kolmogorov, Mikhail
Lelliott, Chris J.
Logan, Darren W.
Loveland, Jane
Mathews, Clayton E.
Mott, Richard
Muir, Paul
Nachtweide, Stefanie
Navarro, Fabio C. P.
Odom, Duncan T.
Park, Naomi
Pelan, Sarah
Pham, Son K.
Quail, Mike
Reinholdt, Laura
Romoth, Lars
Shirley, Lesley
Sisu, Cristina
Sjoberg-Herrera, Marcela
Stanke, Mario
Steward, Charles
Thomas, Mark
Threadgold, Glen
Thybert, David
Torrance, James
Wong, Kim
Wood, Jonathan
Yalcin, Binnaz
Yang, Fengtang
Adams, David J.
Paten, Benedict
Keane, Thomas M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6205630
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6205630
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-018-0223-8
