TMEM173 variants and potential importance to human biology and disease
TMEM173 variants and potential importance to human biology and disease
About this item
Full title
Author / Creator
Patel, Seema and Jin, Lei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
TMEM173
gene encodes the protein STING (stimulator of interferon genes), a key player in host defense against pathogens. Mutations in the human
TMEM173
gene cause a life-threatening auto-inflammatory disease called SAVI (STING-associated vasculopathy with onset in infancy). Human STING is also a promising therapeutic target for cancers and...
Alternative Titles
Full title
TMEM173 variants and potential importance to human biology and disease
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6212339
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6212339
Other Identifiers
ISSN
1466-4879
E-ISSN
1476-5470
DOI
10.1038/s41435-018-0029-9
