Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver ma...
Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2−/− mice
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Multi drug resistance protein 2 knockout mice (
Mdr2
−/−
) are a mouse model of chronic liver inflammation and inflammation-induced tumour development. Here we investigated the kinetics of early heme oxygenase 1 (HO-1) induction on inflammation, tumour development, and DNA damage in
Mdr2
−/−
mice. HO-1 was induced by intraperitone...
Alternative Titles
Full title
Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2−/− mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6214975
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6214975
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-33233-0
