Systematic analysis of complex genetic interactions
Systematic analysis of complex genetic interactions
About this item
Full title
Author / Creator
Kuzmin, Elena , VanderSluis, Benjamin , Wang, Wen , Tan, Guihong , Deshpande, Raamesh , Chen, Yiqun , Usaj, Matej , Balint, Attila , Mattiazzi Usaj, Mojca , van Leeuwen, Jolanda , Koch, Elizabeth N , Pons, Carles , Dagilis, Andrius J , Pryszlak, Michael , Wang, Jason Zi Yang , Hanchard, Julia , Riggi, Margot , Xu, Kaicong , Heydari, Hamed , San Luis, Bryan-Joseph , Shuteriqi, Ermira , Zhu, Hongwei , Van Dyk, Nydia , Sharifpoor, Sara , Costanzo, Michael , Loewith, Robbie , Caudy, Amy , Bolnick, Daniel , Brown, Grant W , Andrews, Brenda J , Boone, Charles and Myers, Chad L
Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: The American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
To systematically explore complex genetic interactions, we constructed ~200,000 yeast triple mutants and scored negative trigenic interactions. We selected double-mutant query genes across a broad spectrum of biological processes, spanning a range of quantitative features of the global digenic interaction network and tested for a genetic interactio...
Alternative Titles
Full title
Systematic analysis of complex genetic interactions
Authors, Artists and Contributors
Author / Creator
VanderSluis, Benjamin
Wang, Wen
Tan, Guihong
Deshpande, Raamesh
Chen, Yiqun
Usaj, Matej
Balint, Attila
Mattiazzi Usaj, Mojca
van Leeuwen, Jolanda
Koch, Elizabeth N
Pons, Carles
Dagilis, Andrius J
Pryszlak, Michael
Wang, Jason Zi Yang
Hanchard, Julia
Riggi, Margot
Xu, Kaicong
Heydari, Hamed
San Luis, Bryan-Joseph
Shuteriqi, Ermira
Zhu, Hongwei
Van Dyk, Nydia
Sharifpoor, Sara
Costanzo, Michael
Loewith, Robbie
Caudy, Amy
Bolnick, Daniel
Brown, Grant W
Andrews, Brenda J
Boone, Charles
Myers, Chad L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6215713
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6215713
Other Identifiers
ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.aao1729
