Systematic analysis of complex genetic interactions
Systematic analysis of complex genetic interactions
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Author / Creator
Kuzmin, Elena , VanderSluis, Benjamin , Wang, Wen , Tan, Guihong , Deshpande, Raamesh , Chen, Yiqun , Usaj, Matej , Balint, Attila , Mattiazzi Usaj, Mojca , van Leeuwen, Jolanda , Koch, Elizabeth N. , Pons, Carles , Dagilis, Andrius J. , Pryszlak, Michael , Wang, Jason Zi Yang , Hanchard, Julia , Riggi, Margot , Xu, Kaicong , Heydari, Hamed , San Luis, Bryan-Joseph , Shuteriqi, Ermira , Zhu, Hongwei , Van Dyk, Nydia , Sharifpoor, Sara , Costanzo, Michael , Loewith, Robbie , Caudy, Amy , Bolnick, Daniel , Brown, Grant W. , Andrews, Brenda J. , Boone, Charles and Myers, Chad L.
Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: The American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
To dissect the genotype-phenotype landscape of a cell, it is necessary to understand interactions between genes. Building on the digenic protein-protein interaction network, Kuzmin
et al.
created a trigenic landscape of yeast by using a synthetic genetic array (see the Perspective by Walhout). Triple-mutant analyses indicated that the majorit...
Alternative Titles
Full title
Systematic analysis of complex genetic interactions
Authors, Artists and Contributors
Author / Creator
VanderSluis, Benjamin
Wang, Wen
Tan, Guihong
Deshpande, Raamesh
Chen, Yiqun
Usaj, Matej
Balint, Attila
Mattiazzi Usaj, Mojca
van Leeuwen, Jolanda
Koch, Elizabeth N.
Pons, Carles
Dagilis, Andrius J.
Pryszlak, Michael
Wang, Jason Zi Yang
Hanchard, Julia
Riggi, Margot
Xu, Kaicong
Heydari, Hamed
San Luis, Bryan-Joseph
Shuteriqi, Ermira
Zhu, Hongwei
Van Dyk, Nydia
Sharifpoor, Sara
Costanzo, Michael
Loewith, Robbie
Caudy, Amy
Bolnick, Daniel
Brown, Grant W.
Andrews, Brenda J.
Boone, Charles
Myers, Chad L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6215713
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6215713
Other Identifiers
ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.aao1729
