Near-atomic model of microtubule-tau interactions
Near-atomic model of microtubule-tau interactions
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Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: The American Association for the Advancement of Science
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Scope and Contents
Contents
Alzheimer's disease is a major cause of death in the elderly. Disease progression is associated with the accumulation of neurofibrillary tangles composed of tau, a protein important for neuronal development and function. Tangle formation is preceded by phosphorylation events that cause tau to dissociate from its native binding partner, microtubules...
Alternative Titles
Full title
Near-atomic model of microtubule-tau interactions
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225777
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225777
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aat1780