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Near-atomic model of microtubule-tau interactions

Near-atomic model of microtubule-tau interactions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225777

Near-atomic model of microtubule-tau interactions

About this item

Full title

Near-atomic model of microtubule-tau interactions

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-06, Vol.360 (6394), p.1242-1246

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Alzheimer's disease is a major cause of death in the elderly. Disease progression is associated with the accumulation of neurofibrillary tangles composed of tau, a protein important for neuronal development and function. Tangle formation is preceded by phosphorylation events that cause tau to dissociate from its native binding partner, microtubules...

Alternative Titles

Full title

Near-atomic model of microtubule-tau interactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225777

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225777

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aat1780

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