Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved acros...
Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
FoxP3⁺ T regulatory (Treg) cells are central elements of immunologic tolerance. They are abundant in many tumors, where they restrict potentially favorable antitumor responses. We used a three-pronged strategy to identify genes related to the presence and function of Tregs in the tumor microenvironment. Gene expression profiles were generated from...
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Full title
Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6233093
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6233093
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1810580115
