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Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development

Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6233116

Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development

About this item

Full title

Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.E10615-E10624

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Codevelopment of the lungs and heart underlies key evolutionary innovations in the transition to terrestrial life. Cardiac specializations that support pulmonary circulation, including the atrial septum, are generated by second heart field (SHF) cardiopulmonary progenitors (CPPs). It has been presumed that transcription factors required in the SHF...

Alternative Titles

Full title

Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6233116

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6233116

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1811624115

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