OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans
OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans
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Full title
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Organic cation transporter 3 (OCT3) is expressed in various organs in humans and plays an important role in the transport of organic cations and drugs including metformin. In this study, we identified genetic variations of the
OCT3
promoter and functionally characterized each variant by
in vitro
assays. Next, the association between the...
Alternative Titles
Full title
OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6240047
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6240047
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-35322-6
