Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancrea...
Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer
About this item
Full title
Author / Creator
Australian Pancreatic Cancer Genome Initiative (APGI) , Chou, Angela , Froio, Danielle , Nagrial, Adnan M , Parkin, Ashleigh , Murphy, Kendelle J , Chin, Venessa T , Wohl, Dalia , Steinmann, Angela , Stark, Rhys , Drury, Alison , Walters, Stacey N , Vennin, Claire , Burgess, Andrew , Pinese, Mark , Chantrill, Lorraine A , Cowley, Mark J , Molloy, Timothy J , Waddell, Nicola , Johns, Amber , Grimmond, Sean M , Chang, David K , Biankin, Andrew V , Sansom, Owen J , Morton, Jennifer P , Grey, Shane T , Cox, Thomas R , Turchini, John , Samra, Jaswinder , Clarke, Stephen J , Timpson, Paul , Gill, Anthony J and Pajic, Marina
Publisher
England: BMJ Publishing Group LTD
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group LTD
Subjects
More information
Scope and Contents
Contents
ObjectiveExtensive molecular heterogeneity of pancreatic ductal adenocarcinoma (PDA), few effective therapies and high mortality make this disease a prime model for advancing development of tailored therapies. The p16-cyclin D-cyclin-dependent kinase 4/6-retinoblastoma (RB) protein (CDK4) pathway, regulator of cell proliferation, is deregulated in...
Alternative Titles
Full title
Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer
Authors, Artists and Contributors
Author / Creator
Chou, Angela
Froio, Danielle
Nagrial, Adnan M
Parkin, Ashleigh
Murphy, Kendelle J
Chin, Venessa T
Wohl, Dalia
Steinmann, Angela
Stark, Rhys
Drury, Alison
Walters, Stacey N
Vennin, Claire
Burgess, Andrew
Pinese, Mark
Chantrill, Lorraine A
Cowley, Mark J
Molloy, Timothy J
Waddell, Nicola
Johns, Amber
Grimmond, Sean M
Chang, David K
Biankin, Andrew V
Sansom, Owen J
Morton, Jennifer P
Grey, Shane T
Cox, Thomas R
Turchini, John
Samra, Jaswinder
Clarke, Stephen J
Timpson, Paul
Gill, Anthony J
Pajic, Marina
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6241608
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6241608
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2017-315144
