Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo
Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo
About this item
Full title
Author / Creator
DiTommaso, Tia , Cole, Julie M. , Cassereau, Luke , Buggé, Joshua A. , Hanson, Jacquelyn L. Sikora , Bridgen, Devin T. , Stokes, Brittany D. , Loughhead, Scott M. , Beutel, Bruce A. , Gilbert, Jonathan B. , Nussbaum, Kathrin , Sorrentino, Antonio , Toggweiler, Janine , Schmidt, Tobias , Gyuelveszi, Gabor , Bernstein, Howard and Sharei, Armon
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The translational potential of cell-based therapies is often limited by complications related to effectively engineering and manufacturing functional cells. While the use of electroporation is widespread, the impact of electroporation on cell state and function has yet to be fully characterized. Here, we use a genome-wide approach to study optimize...
Alternative Titles
Full title
Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo
Authors, Artists and Contributors
Author / Creator
Cole, Julie M.
Cassereau, Luke
Buggé, Joshua A.
Hanson, Jacquelyn L. Sikora
Bridgen, Devin T.
Stokes, Brittany D.
Loughhead, Scott M.
Beutel, Bruce A.
Gilbert, Jonathan B.
Nussbaum, Kathrin
Sorrentino, Antonio
Toggweiler, Janine
Schmidt, Tobias
Gyuelveszi, Gabor
Bernstein, Howard
Sharei, Armon
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6243275
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6243275
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1809671115
