DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury
DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Patients with acute kidney injury (AKI) frequently require kidney transplantation and supportive therapies, such as rehydration and dialysis. Here, we show that radiolabelled DNA origami nanostructures (DONs) with rectangular, triangular and tubular shapes accumulate preferentially in the kidneys of healthy mice and mice with rhabdomyolysis-induced...
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Full title
DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6258029
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6258029
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ISSN
2157-846X
E-ISSN
2157-846X
DOI
10.1038/s41551-018-0317-8
