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Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ...

Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6266872

Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ1.1 (AKR6A8) subunit of voltage-gated potassium channel

About this item

Full title

Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ1.1 (AKR6A8) subunit of voltage-gated potassium channel

Publisher

New York: Springer US

Journal title

Molecular and cellular biochemistry, 2017-12, Vol.436 (1-2), p.71-78

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

We previously demonstrated the role of Kvβ1.1 subunit of voltage-activated potassium channel in heart for its sensory roles in detecting changes in NADH/NAD and modulation of ion channel. However, the pharmacological role for the association of Kvβ1 via its binding to ligands such as cortisone and its analogs remains unknown. Therefore, we investig...

Alternative Titles

Full title

Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ1.1 (AKR6A8) subunit of voltage-gated potassium channel

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6266872

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6266872

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-017-3079-9

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