Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice
Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice
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Publisher
Cham: Elsevier Inc
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Language
English
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Publisher
Cham: Elsevier Inc
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Contents
Proteolytic cleavage of the amyloid precursor protein (APP) into the Aβ peptide has been an extensively researched mechanism for Alzheimer's disease, but the normal function of the protein is less understood. APP functions to regulate neuronal iron content by stabilizing the surface presentation of ferroportin—the only iron exporter channel of cell...
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Full title
Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6277293
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6277293
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ISSN
1878-7479,1933-7213
E-ISSN
1878-7479
DOI
10.1007/s13311-018-0656-x
