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Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation...

Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6279066

Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse

About this item

Full title

Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse

Publisher

United States: Society for the Study of Reproduction

Journal title

Biology of reproduction, 2017-04, Vol.96 (4), p.816-828

Language

English

Formats

Publication information

Publisher

United States: Society for the Study of Reproduction

More information

Scope and Contents

Contents

Spermatogonial stem cells must balance self-renewal with production of transit-amplifying progenitors that differentiate in response to retinoic acid (RA) before entering meiosis. This self-renewal vs. differentiation fate decision is critical for maintaining tissue homeostasis, as imbalances cause defects that can lead to human testicular cancer o...

Alternative Titles

Full title

Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6279066

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6279066

Other Identifiers

ISSN

0006-3363

E-ISSN

1529-7268

DOI

10.1093/biolre/iox022

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