Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation...
Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse
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Publisher
United States: Society for the Study of Reproduction
Journal title
Language
English
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Publisher
United States: Society for the Study of Reproduction
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Scope and Contents
Contents
Spermatogonial stem cells must balance self-renewal with production of transit-amplifying progenitors that differentiate in response to retinoic acid (RA) before entering meiosis. This self-renewal vs. differentiation fate decision is critical for maintaining tissue homeostasis, as imbalances cause defects that can lead to human testicular cancer o...
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Full title
Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6279066
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6279066
Other Identifiers
ISSN
0006-3363
E-ISSN
1529-7268
DOI
10.1093/biolre/iox022