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Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6279925

Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

About this item

Full title

Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-12, Vol.8 (1), p.17597-14, Article 17597

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neuronal signal transduction shapes brain function and malfunction may cause mental disorders. Despite the existence of functional genomics screens for proliferation and toxicity, neuronal signalling has been difficult to address so far. To overcome this limitation, we developed a pooled screening assay which combines barcoded activity reporters wi...

Alternative Titles

Full title

Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6279925

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6279925

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-36008-9

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