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Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowme...

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowme...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6281319

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

About this item

Full title

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2018-12, Vol.7

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

A normal endowment of nephrons in the mammalian kidney requires a balance of nephron progenitor self-renewal and differentiation throughout development. Here, we provide evidence for a novel action of ureteric branch tip-derived Wnt11 in progenitor cell organization and interactions within the nephrogenic niche, ultimately determining nephron endow...

Alternative Titles

Full title

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6281319

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6281319

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.40392

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