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Radiotherapy induces responses of lung cancer to CTLA-4 blockade

Radiotherapy induces responses of lung cancer to CTLA-4 blockade

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6286242

Radiotherapy induces responses of lung cancer to CTLA-4 blockade

About this item

Full title

Radiotherapy induces responses of lung cancer to CTLA-4 blockade

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2018-12, Vol.24 (12), p.1845-1851

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Focal radiation therapy enhances systemic responses to anti-CTLA-4 antibodies in preclinical studies and in some patients with melanoma
1

3
, but its efficacy in inducing systemic responses (abscopal responses) against tumors unresponsive to CTLA-4 blockade remained uncertain. Radiation therapy promotes the activation of anti-tumor T...

Alternative Titles

Full title

Radiotherapy induces responses of lung cancer to CTLA-4 blockade

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6286242

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6286242

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-018-0232-2

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