Automethylation-induced conformational switch in Clr4/Suv39h maintains epigenetic stability
Automethylation-induced conformational switch in Clr4/Suv39h maintains epigenetic stability
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English
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Histone H3 lysine 9 methylation (H3K9me) mediates heterochromatic gene silencing and is important for genome stability and regulation of gene expression
1
–
4
. The establishment and epigenetic maintenance of heterochromatin involve the recruitment of H3K9 methyltransferases to specific sites on DNA followed by the recognition of pre-ex...
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Automethylation-induced conformational switch in Clr4/Suv39h maintains epigenetic stability
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6287498
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6287498
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0398-2
