T-bet: a bridge between innate and adaptive immunity
T-bet: a bridge between innate and adaptive immunity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
T-bet is expressed in many different cell types of the innate and adaptive immune system in both myeloid and lymphoid lineages.
T-bet expression arose early in evolution, before the appearance of the adaptive immune system, which suggests that its function in B cells and T cells may partly reflect coopted transcriptional pathways.<...
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Full title
T-bet: a bridge between innate and adaptive immunity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6290922
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6290922
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ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri3536
