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S1P1 receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphing...

S1P1 receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphing...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294635

S1P1 receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphingosine 1-phosphate, FTY720-P, phorbol esters, and paroxetine

About this item

Full title

S1P1 receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphingosine 1-phosphate, FTY720-P, phorbol esters, and paroxetine

Publisher

Portland Press Ltd

Journal title

Bioscience reports, 2018-12, Vol.38 (6)

Language

English

Formats

Publication information

Publisher

Portland Press Ltd

More information

Scope and Contents

Contents

Sphingosine 1-phosphate (S1P) and FTY720-phosphate (FTYp) increased intracellular calcium in cells expressing S1P1 mCherry-tagged receptors; the synthetic agonist was considerably less potent. Activation of protein kinase C by phorbol myristate acetate (PMA) blocked these effects. The three agents induced receptor phosphorylation and internalizatio...

Alternative Titles

Full title

S1P1 receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphingosine 1-phosphate, FTY720-P, phorbol esters, and paroxetine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294635

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294635

Other Identifiers

ISSN

0144-8463

E-ISSN

1573-4935

DOI

10.1042/BSR20181612

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