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Intrinsic cellular chirality regulates left–right symmetry breaking during cardiac looping

Intrinsic cellular chirality regulates left–right symmetry breaking during cardiac looping

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294912

Intrinsic cellular chirality regulates left–right symmetry breaking during cardiac looping

About this item

Full title

Intrinsic cellular chirality regulates left–right symmetry breaking during cardiac looping

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (50), p.E11568-E11577

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The vertebrate body plan is overall symmetrical but left–right (LR) asymmetric in the shape and positioning of internal organs. Although several theories have been proposed, the biophysical mechanisms underlying LR asymmetry are still unclear, especially the role of cell chirality, the LR asymmetry at the cellular level, on organ asymmetry. Here wi...

Alternative Titles

Full title

Intrinsic cellular chirality regulates left–right symmetry breaking during cardiac looping

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294912

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1808052115

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