Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture
Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Tumorigenesis depends on intricate interactions between genetically altered tumor cells and their surrounding microenvironment. While oncogenic drivers in lung squamous carcinoma (LUSC) have been described, the role of stroma in modulating tissue architecture, particularly cell polarity, remains unclear. Here, we report the establishment of a 3D co...
Alternative Titles
Full title
Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294935
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294935
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1803718115
