Structure and architecture of immature and mature murine leukemia virus capsids
Structure and architecture of immature and mature murine leukemia virus capsids
About this item
Full title
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Retroviruses assemble and bud from infected cells in an immature form and require proteolytic maturation for infectivity. The CA (capsid) domains of the Gag polyproteins assemble a protein lattice as a truncated sphere in the immature virion. Proteolytic cleavage of Gag induces dramatic structural rearrangements; a subset of cleaved CA subsequently...
Alternative Titles
Full title
Structure and architecture of immature and mature murine leukemia virus capsids
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294937
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294937
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1811580115
