Basophils trigger emphysema development in a murine model of COPD through IL-4–mediated generation o...
Basophils trigger emphysema development in a murine model of COPD through IL-4–mediated generation of MMP-12–producing macrophages
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. It has generally been considered a non-Th2-type lung disorder, characterized by progressive airflow limitation with inflammation and emphysema, but its cellular and molecular mechanism remains ill defined, compared with that of asthma characterized...
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Basophils trigger emphysema development in a murine model of COPD through IL-4–mediated generation of MMP-12–producing macrophages
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6305004
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6305004
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1813927115