OATP1B3 (699G>A) and CYP2C92, 3 significantly influenced the transport and metabolism of glibenclami...
OATP1B3 (699G>A) and CYP2C92, 3 significantly influenced the transport and metabolism of glibenclamide and glipizide
About this item
Full title
Author / Creator
Yang, Fayou , Liu, Linlin , Chen, Lin , Liu, Mingyi , Liu, Fanglan , Xiong, Yuqing , Hu, Xiao and Xia, Chunhua
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Glibenclamide and glipizide show large substantial inter-individual variation in clinical efficacy, which may be resulted from the genetic differences of metabolic enzymes and transporters in individuals. This study purposed to investigate the effect of OATP1B3 and CYP2C9 genetic polymorphisms on the transport and metabolism of glibenclamide and gl...
Alternative Titles
Full title
OATP1B3 (699G>A) and CYP2C92, 3 significantly influenced the transport and metabolism of glibenclamide and glipizide
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6305483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6305483
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-36212-7
